Lois Griffin (seasons 8-present)

Lois Patrice Pewterschmidt-Griffin (born February 18, 1975) is the deuteragonist in the FOX animated TV series Family Guy. Originally she was a protagonist, but as she became darker, despite being one of the protagonists, she does have several episodes where she has an antagonistic role.

She is voiced by Alex Borstein, who is well-known for her portrayal of Ms. Bonnie Swann on the hit satirical comedy show MADtv.

Why She Sucks

 * 1) Brick (Rowdyruff Boys), Boomer (Rowdyruff Boys), Butch (Rowdyruff Boys), Olga (Dexter's Lab) & Sarah (Caillou) all need to be transformed into unfertilized egg's & sucked into lois's uteris.